Aesthetic Chills and Self-Transcendence: Another step toward the democratization of mystical experience

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Christov-Moore, L., Schoeller, F., Lynch, C., Sacchet, M., & Reggente, N. (2024). Self-transcendence accompanies aesthetic chills. PLOS Mental Health, 1(5), e0000125. https://doi.org/10.1371/journal.pmen.0000125

Christov-Moore, Leonardo, et al. “Self-transcendence accompanies aesthetic chills.” PLOS Mental Health, vol. 1, no. 5, Oct. 2024, p. e0000125. https://doi.org/10.1371/journal.pmen.0000125.

@article{Christov-Moore_Schoeller_Lynch_Sacchet_Reggente_2024, title={Self-transcendence accompanies aesthetic chills}, volume={1}, url={https://doi.org/10.1371/journal.pmen.0000125}, DOI={10.1371/journal.pmen.0000125}, number={5}, journal={PLOS Mental Health}, author={Christov-Moore, Leonardo and Schoeller, Felix and Lynch, Caitlin and Sacchet, Matthew and Reggente, Nicco}, year={2024}, month=oct, pages={e0000125}, language={en} }


Some of the smallest things are the most important. These small, important things and events can escape our notice and study for a long time. They are special precisely because they are small and, paradoxically, everywhere. An incredibly important and heretofore unknown component of the human circulatory system went unnoticed until just the last decade, despite thousands of years of studying human anatomy, because it was wispy, small, and everywhere. Such is the case with the aesthetic chills phenomenon, which few people even think to name or pay attention to, yet which all of us experience. In our search to democratize non-ordinary, mystical, transformative experiences, it may prove to be a key ally—a living biological demonstration of the fact that aesthetics began not in commerce, but in religion and our encounter with the transcendent.

Over the last year, our lab has found that aesthetic chills can not only be reliably evoked, but they also show many of the classical properties of transformative psychedelic experiences. They seem to alleviate depressive symptoms, maybe even reverse maladaptive, deep-seated beliefs, and seem deeply tied to our deepest beliefs and insights. In this study, we sought to examine whether the experience of aesthetic chills could, in fact, bear the characteristics of a tiny, self-transcendent, mystical experience.

To investigate this, we exposed 3,000 people from all over California to a series of songs, videos, and speeches that previous studies had found to consistently cause chills in a majority of people examined. We had them fill out questionnaires that examined their demographic qualities, personality traits, proneness to religious experiences and thinking, and even their political orientation. Then we showed them the video or song and had them fill out another series of questionnaires, assessing their mood, asking them whether they got chills and how intense they were, and importantly, asking if they experienced any of the classical three components of a crucial state known as self-transcendence.

A brief aside on what self-transcendence is: first coined in the 1980s within nursing literature, it was a trait used to describe a state or proclivity that seemed to correlate with and predict long-term health and well-being among people approaching old age. The state was characterized by:

1. Feelings of becoming one with everything, of ego dissolving

2. Feeling connected to one’s deeper self, to the world, and to other people

3. A sense of moral elevation, a motivation to live a nobler or more virtuous life, and a sense of compassion towards others

As it turns out, self-transcendence predicts well-being, resilience to adverse events, and prosocial, empathetic behavior in people of all ages, nationalities, creeds, and orientations. Importantly, having a self-transcendent event—whether it be a major life event, a psychedelic experience, an advanced meditative state, or immersion in nature—has been shown to cause greater well-being, greater resilience, and a greater inclination to help others.

What we found and replicated in independent samples in both California and Texas, as well as in yet another recent replication (in total, some 5,000 people), was an incredibly significant and robust relationship between the experience of chills, its intensity, and self-transcendence. Over and over again, with remarkable consistency, if a person experiences chills and to the extent to which they experience them, they will also report feeling that their ego is dissolved, that they are connected to the world and their deeper selves, and that they feel motivated to live in a kinder, nobler, more virtuous way.

In fact, adding chill-inducing music to a guided meditation increases people’s perception of its self-transcendent qualities and enhances the impact and sense of immersion people report from the meditation. What these findings reveal is that this small but ubiquitous human experience may be a microcosm of the transformative, mystical experiences often considered to be elusive or difficult to achieve for most of the population.

The more we can harness these little experiences and combine them, the more we may be able to bring these central meaning-making experiences—once thought to be the sole domain of psychedelics, religion, or advanced meditation—to that vast mass of people who, in our modern era, are perhaps too skeptical for religion and averse to the psychedelic experience. This could help improve their lives, improve their behavior towards others, and sustain a sense of meaning otherwise all too often taken up by consumerism or demagogues.

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Empathy from Dissimilarity In Neural Responses To Touch and Pain

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Lulla, R., Christov-Moore, L., Vaccaro, A., Reggente, N., Iacoboni, M., & Kaplan, J. (2024). Empathy from Dissimilarity: Multivariate Pattern Analysis of Neural Activity During Observation of Somatosensory Experience. Imaging Neuroscience. https://doi.org/10.1162/imag_a_00110

Lulla, Rishi, et al. “Empathy from Dissimilarity: Multivariate Pattern Analysis of Neural Activity During Observation of Somatosensory Experience.” Imaging Neuroscience, Jan. 2024, doi:10.1162/imag_a_00110.

@article{Lulla_Christov-Moore_Vaccaro_Reggente_Iacoboni_Kaplan_2024, title={Empathy from Dissimilarity: Multivariate Pattern Analysis of Neural Activity During Observation of Somatosensory Experience}, url={https://doi.org/10.1162/imag_a_00110}, DOI={10.1162/imag_a_00110}, journal={Imaging Neuroscience}, author={Lulla, Rishi and Christov-Moore, Leonardo and Vaccaro, A. and Reggente, Nicco and Iacoboni, Marco and Kaplan, Jonas}, year={2024}, month=jan }

Empathy: A Deeper Look

Empathy involves both understanding and sharing in the states of others. It’s been relatively established that empathy is related to our ability to simulate and internalize another’s experience as if it is happening to us, referred to as the ‘simulationist’ theory of empathy. However, how these simulations translate into empathic ability remains unclear. In an article titled ‘Empathy from Dissimilarity: Multivariate Pattern Analysis of Neural Activity during Observation of Others’ Somatosensory States’, researchers from the University of Southern California and the Institute for Advanced Consciousness Studies investigate the relationship between internal simulations and empathic traits. They question whether the importance of these simulations depends on not only the strength of the simulation but more so the distinguishability across simulated states.

Brain Patterns and Simulation

To evaluate this theory using patterns of neural activity, researchers recruited 70 healthy participants to undergo MRI imaging while observing videos intended to simulate certain sensory states. The videos consisted of a hand experiencing painful and tactile stimulation and a hand in isolation as control. They used advanced multivariate analysis techniques to delve into the granularity of neural activity, such as differences in neural patterns when simulating pain versus touch. This allowed them to probe whether the key to the simulationist theory lay within the relationship between differences in neural patterns of simulated states and empathic ability.

Dissimilarity as a Key Factor

This article evaluates empathy through the lens of ‘pattern dissimilarity’ rather than overall activation during observed experiences of others, analyzing areas of the brain in which pattern dissimilarity was predictive of empathic traits. This proved to be more useful than traditional methods of evaluating neural responses that rely on average activation levels rather than activity patterns. Researchers discovered that pattern dissimilarity was predictive of empathic traits in the same areas of the brain that would be engaged if the participant was experiencing the observed stimulation themselves. This sheds light on the intricacies of somatosensation, our bodily perception of the senses, that contribute to empathic ability.

Implications for Understanding Empathy

These findings show how pattern dissimilarity may provide deeper information than traditional analysis methods when researching cognitive functions such as empathy. Researchers suggest that the distinguishability of simulated internal states in somatosensory areas of the brain is predictive of an individual’s sympathetic reactions to the distress of others. Perhaps it’s not only the level of brain activity during internal simulation, but more so the uniqueness and distinguishability of that brain activity that leads us to feel for and understand others.

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neural correlates of chills as shown by a frozen brain

The neural correlates of chills: How bodily sensations shape emotional experiences

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Schoeller, F., Jain, A., Pizzagalli, D. A., & Reggente, N. (2024). The neurobiology of aesthetic chills: How bodily sensations shape emotional experiences. Cognitive, Affective, & Behavioral Neuroscience. https://doi.org/10.3758/s13415-024-01168-x

Schoeller, Félix, Abhinandan Jain, et al. “The neurobiology of aesthetic chills: How bodily sensations shape emotional experiences.” Cognitive, Affective, & Behavioral Neuroscience, Feb. 2024, doi:10.3758/s13415-024-01168-x.

@article{Schoeller_Jain_Pizzagalli_Reggente_2024, title={The neurobiology of aesthetic chills: How bodily sensations shape emotional experiences}, url={https://doi.org/10.3758/s13415-024-01168-x}, DOI={10.3758/s13415-024-01168-x}, journal={Cognitive, Affective, & Behavioral Neuroscience}, author={Schoeller, Félix and Jain, Abhinandan and Pizzagalli, Diego A. and Reggente, Nicco}, year={2024}, month=feb }

Neural Correlates of Chills: How the Brain Creates a Powerful Emotional Response

Aesthetic chills are a universal emotional response characterized by shivers and goosebumps in reaction to specific rewarding or threatening stimuli, such as music, films, or speech. What makes this phenomenon so intriguing is that it simultaneously involves subjective feelings and measurable physical sensations, providing a tangible link between the mind and body.

The Role of Brain Regions and Networks

Recent research has shed light on the specific brain regions and networks involved in the experience of aesthetic chills. Understanding the neural correlates of chills helps us delve into fascinating questions about the mind-body connection.

Our review highlights key questions that aesthetic chills can help us answer: How precisely do bodily sensations influence emotional experiences? What is the role of prediction and uncertainty in shaping our feelings? And how does the brain balance processing rewards versus threats?

neural correlates of chills are vast and span the cerebrum, cerebellum, and brainstem

The Mesocorticolimbic System: A Key Player in Chills

By synthesizing evidence from neuroimaging studies, we propose that aesthetic chills engage a distinct brain network involving the mesocorticolimbic system. This network includes regions like the ventral tegmental area (VTA), nucleus accumbens (NAcc), amygdala (AMG), and frontal areas such as the orbitofrontal cortex (OFC) and ventromedial prefrontal cortex (vmPFC). Crucially, the VTA releases dopamine, a neurotransmitter critical for reward processing and motivation, throughout these regions.

Chills, Reward, Learning, and the Brain’s Predictions

neural correlates of chills seem to depend on the learning rate

We suggest that aesthetic chills may correspond to peaks in consummatory pleasure, marking the transition from the “wanting” phase of reward to the “liking” and “learning” phases. This perspective aligns with the observation that chills often occur during the culmination of an aesthetic experience, such as the resolution of a narrative or musical tension.

neural correlates of chills seem associated with the anticipation and reward response.

Interoception and the Insula

The involvement of the insula, a region linked to interoception (the perception of internal bodily states), highlights the importance of peripheral signals in shaping the emotional quality of chills. This is further supported by findings that manipulating bodily sensations, such as enhancing the feeling of cold, can intensify the experience of chills and its downstream effects on cognition.

Individual Differences and the Experience of Chills

Interestingly, our susceptibility to aesthetic chills seems to be influenced by individual differences in personality traits like openness to experience and absorption, as well as biological factors such as gene variants affecting neurotransmitter function. This suggests that our propensity for chills is shaped by a complex interplay of psychological and neurobiological factors.

Dopamine, Prediction Errors, and Learning

We propose that the neurotransmitter dopamine plays a key role in aesthetic chills by encoding the precision of our brain’s predictions. When an aesthetic stimulus violates our expectations in a way that is ultimately rewarding, dopamine release signals the need to update our predictions, enhancing memory consolidation and learning. This process may underlie the heightened attention and memory effects observed during chills.

Mental Health Implications

Understanding the neurobiology of aesthetic chills has important implications for mental health. Dysfunctional precision encoding of prediction errors by dopamine is implicated in conditions like schizophrenia, depression, and addiction. Preliminary evidence suggests that experiencing aesthetic chills may help mitigate anhedonia (loss of pleasure) in depression by improving reward learning and shifting maladaptive self-beliefs. The therapeutic potential of chills lies in their ability to promote positive emotional states and cognitive flexibility.

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this predicting chills image shows a row of people and one with frost on their glasses

Predicting Chills – Characterizing Individual Differences in Peak Emotional Response

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Schoeller, F., Christov-Moore, L., Lynch, C., Diot, T., & Reggente, N. (2024). Predicting Individual Differences in Peak Emotional Response. PNAS Nexus, 3(3). https://doi.org/10.1093/pnasnexus/pgae066

Schoeller, Félix, Leonardo Christov-Moore, et al. “Predicting Individual Differences in Peak Emotional Response.” PNAS Nexus, vol. 3, no. 3, Feb. 2024, https://doi.org/10.1093/pnasnexus/pgae066.

@article{Schoeller_Christov-Moore_Lynch_Diot_Reggente_2024, title={Predicting Individual Differences in Peak Emotional Response}, volume={3}, url={https://doi.org/10.1093/pnasnexus/pgae066}, DOI={10.1093/pnasnexus/pgae066}, number={3}, journal={PNAS Nexus}, author={Schoeller, Félix and Christov-Moore, Leonardo and Lynch, Caitlin and Diot, Thomas and Reggente, Nicco}, year={2024}, month=feb }

Predicting Chills: Unraveling the Factors Behind a Powerful Emotional Response

Have you ever felt a shiver run down your spine when deeply moved by a piece of music or a scene in a film? Those “aesthetic chills” offer a fascinating glimpse into the interplay of our emotions and our individual experiences. In a recent study published in PNAS Nexus, we aimed to understand what makes some people more likely to feel these chills.

The Study Design

Our approach was multifaceted:

  • Stimuli Selection: We used innovative data mining techniques on social media platforms to curate a database of stimuli with a proven track record of inducing chills.
  • Diverse Participants: We exposed a diverse group of over 2,900 participants from Southern California to these stimuli. Data on their demographics, personality traits, and emotional responses were carefully collected.

Key Findings: Who’s Most Likely to Experience Chills

Our results were illuminating:

  • Demographics: Certain demographic factors, such as being middle-aged, highly educated, and male, were associated with a greater likelihood of experiencing chills.
  • Personality’s Impact: We also identified specific personality traits, like extraversion and conscientiousness, that were linked to more intense chills responses.
  • Microcultures and Resonance: Perhaps the most intriguing finding was the use of latent class analysis to uncover hidden “microcultures.” These subgroups, characterized by specific combinations of demographic and psychological attributes, were significantly more likely to experience chills. This points to the role of cultural resonance in shaping these emotional experiences.
predicting chills is hard - this image shows a bunch of people in a where's waldo style backdrop all looking at different pieces of content

Predictive Power: Can We Foresee Chills?

We pushed the analysis further by employing machine learning algorithms to see if we could predict the occurrence and intensity of chills based on a combination of personal characteristics. Our models achieved up to 73.5% accuracy in predicting whether someone would experience chills and accounted for 48% of the variance in chills intensity.

The Significance of Our Work

This study has far-reaching implications. By identifying the key factors that shape our susceptibility to aesthetic chills, we open doors to more targeted and personalized approaches to studying these experiences in a laboratory setting. Furthermore, understanding these “chills profiles” could pave the way for using music, art, or other stimuli in therapeutic contexts – perhaps helping reduce symptoms like anhedonia in depression.

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Individual Differences in Aesthetic Chills

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Schoeller, F., Moore, L., Lynch, C., & Reggente, N. (2023c). ChillsDB 2.0: Individual Differences in aesthetic chills among 2,900+ Southern California participants. Scientific Data, 10(1). https://doi.org/10.1038/s41597-023-02816-6

Schoeller, Felix, et al. “ChillsDB 2.0: Individual Differences in Aesthetic Chills Among 2,900+ Southern California Participants.” Scientific data 10.1 (2023): 922.

@article{schoeller2023chillsdb, title={ChillsDB 2.0: Individual Differences in Aesthetic Chills Among 2,900+ Southern California Participants}, author={Schoeller, Felix and Christov Moore, Leo and Lynch, Caite and Reggente, Nicco}, journal={Scientific data}, volume={10}, number={1}, pages={922}, year={2023}, publisher={Nature Publishing Group UK London} }

Understanding Individual Differences in Aesthetic Chills

At IACS, we have been deeply engaged in the scientific exploration of aesthetic chills – those spine-tingling, goosebump-inducing responses evoked by stimuli such as music, films, and stories at large. These responses are recognized as a universal indicator of peak human experiences that transcend cultural boundaries.

Tools for Investigating Aesthetic Chills

One of our main goals is to build an open-source technological infrastructure for researchers to study chills in the lab. Our first output was ChillsDB, a database of audiovisual stimuli designed and validated to reliably induce aesthetic chills in a laboratory setting. This tool represented a breakthrough for the field, enabling researchers to investigate the psychological and neurological foundations of this intense emotional response under controlled conditions.

individual differences in aesthetic chills - this image shows a person viewing different pieces of content to emphasize how different people get chills from different content.

ChillsDB 2.0: Focusing on Individuality

We are now excited to announce the release of ChillsDB 2.0, published in Nature: Scientific Data, which marks a significant expansion of our initial efforts. In this updated version, we have enriched our dataset with inputs from nearly 3,000 diverse participants from Southern California. This enhancement not only includes responses to a selection of stimuli from our original database and new additions but also encompasses comprehensive data on participants’ demographics, personality traits, and emotional states before and after exposure to each stimulus.

The Therapeutic Potential of Aesthetic Chills

ChillsDB 2.0 has already proven to be a foundational resource for examining the therapeutic possibilities of aesthetic chills in treating conditions like depression. By elucidating the mechanisms behind these peak emotional states, we aim to discover novel methods for enhancing mood and introducing new perspectives to both clinical and general populations.

The Path Forward

While significant efforts are still required to comprehensively understand the phenomenology and neurobiology of aesthetic chills and to harness these insights for improving well-being, this new database represents an important step forward.

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Aesthetic chills mitigate maladaptive cognition in depression-- an important finding showcasing the power of positive affect promotion.

Aesthetic chills mitigate maladaptive cognition in depression

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Schoeller, F., Jain, A., Adrien, V., Maes, P., & Reggente, N. (2024). Aesthetic chills mitigate maladaptive cognition in depression. BMC Psychiatry, 24(1). https://doi.org/10.1186/s12888-023-05476-3

“Aesthetic Chills Mitigate Maladaptive Cognition in Depression.” BMC Psychiatry, vol. 24, no. 1, Jan. 2024, https://doi.org/10.1186/s12888-023-05476-3.

@article{Schoeller_Jain_Adrien_Maes_Reggente_2024c, title={Aesthetic chills mitigate maladaptive cognition in depression}, volume={24}, url={https://doi.org/10.1186/s12888-023-05476-3}, DOI={10.1186/s12888-023-05476-3}, number={1}, journal={BMC Psychiatry}, author={Schoeller, Félix and Jain, Abhinandan and Adrien, Vladimir and Maes, Pattie and Reggente, Nicco}, year={2024}, month=jan }

Using peak positive affect (aesthetic chills) to help with depression

In our recent collaboration with Pattie Maes’s Fluid Interfaces group at MIT Media Lab and Dr. Vladimir Adrien from Assistance Publique Hôpitaux de Paris (APHP) in France, we investigated the potential for aesthetic chills to serve as an innovative intervention for major depressive disorder. This effort is a considerable advancement towards the notion of promoting positive affect in depression, which stands in contrast to standard care which is mostly focused on mitigating negative affect.

Instead of focusing on how to help individuals with depression not feel so bad, this work suggests the potential of helping those individuals by presenting them with content so they can feel good.

Aesthetic chills are characterized by sensations like shivers, goosebumps, and tingling that arise in response to emotional experiences with art, music, or nature. We hypothesized that by eliciting chills through validated multimedia stimuli, we could positively influence the core beliefs and self-schemas of individuals with depression. Across two studies with 96 participants diagnosed with major depressive disorder, we engaged participants in randomized sessions involving chill-inducing and neutral control stimuli across visual, auditory, and written modalities. Our results demonstrated that aesthetic chills induced a notable increase in self-acceptance among depressed participants. Chill-inducing stimuli appeared to facilitate positive emotional breakthroughs and shifts in self-perception that could address cognitive distortions related to depression. The data further suggest that aesthetic chills may engage reward-related neural pathways similarly to interventions like psychedelic-assisted therapy.

Individuals with major depressive disorder reported more emotional breakthroughs in their maladaptive cognition (e.g., lack of self-acceptance) when they reported getting chills compared to individuals who viewed the same content, but didn’t get chills. This also scaled as a function of the intensity of those chills.

While preliminary, these findings bring much-needed attention to the potential for aesthetic chills to positively influence core beliefs and schemas related to the self and one’s place in the world. For individuals with depression stemming from early adverse experiences, chill-inducing stimuli could foster emotional catharsis and lasting change to maladaptive self-narratives developed as coping mechanisms. Our research provides initial evidence that the biological processes involved in aesthetic chills can be harnessed for therapeutic ends. Chill-based interventions offer a promising avenue for large-scale study given the ease of dissemination through multimedia experiences.

Looking forward, further research should explore the neurophysiological mechanisms of aesthetic chills and biomarkers that may predict individual responses. Larger clinical trials are needed to investigate optimal protocols and delivery methods for chill-based therapy. We believe aesthetic chills represent an innovative non-pharmacological intervention that warrants greater attention from the psychiatry, psychology, and human-computer interaction communities.

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Interoceptive Technologies for Psychiatric Interventions: A Comprehensive Review

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Schoeller, F., Horowitz, A. H., Jain, A., Maes, P., Reggente, N., Christov-Moore, L., . . . Friston, K. J. (2024). Interoceptive technologies for psychiatric interventions: From diagnosis to clinical applications. Neuroscience & Biobehavioral Reviews, 156, 105478. https://doi.org/10.1016/j.neubiorev.2023.105478

Schoeller, Félix, Adam Haar Horowitz, et al. “Interoceptive Technologies for Psychiatric Interventions: From Diagnosis to Clinical Applications.” Neuroscience & Biobehavioral Reviews, vol. 156, Jan. 2024, p. 105478. https://doi.org/10.1016/j.neubiorev.2023.105478.

@article{Schoeller_Horowitz_Jain_Maes_Reggente_Christov-Moore_Pezzulo_Barca_Allen_Salomon_et al._2024, title={Interoceptive technologies for psychiatric interventions: From diagnosis to clinical applications}, volume={156}, url={https://doi.org/10.1016/j.neubiorev.2023.105478}, DOI={10.1016/j.neubiorev.2023.105478}, journal={Neuroscience & Biobehavioral Reviews}, author={Schoeller, Félix and Horowitz, Adam Haar and Jain, Abhinandan and Maes, Pattie and Reggente, Nicco and Christov-Moore, Leonardo and Pezzulo, Giovanni and Barca, Laura and Allen, Micah and Salomon, Roy and Miller, Mark and Di Lernia, Daniele and Riva, Giuseppe and Tsakiris, Manos and Chalah, Moussa A. and Klein, Arno and Zhang, Ben and Garcia, Teresa and Pollack, Ursula and Trousselard, Marion and Verdonk, Charles and Dumas, Guillaume and Adrien, Vladimir and Friston, Karl J.}, year={2024}, month=jan, pages={105478} }

What Is Interoception?

Interoception refers to our awareness of internal bodily signals like heartbeat, breathing, and digestion. While often overlooked, emerging research is revealing interoception as a fundamental process underlying emotion, cognition, and mental health. A new multidisciplinary review led by IACS senior research scientist Felix Schoeller and published in Neuroscience & Biobehavioral Reviews explores the profound significance of interoception and its potential applications in psychiatric diagnosis and treatment.

Directly manipulating interoceptive signals in experiments has proven challenging due to the highly invasive techniques currently used, like esophageal balloon distension. There is also a lack of standardized, validated measures of interoceptive function across research disciplines as “the lack of correlation across unimodal tests underscores the need for multimodal approaches that assess integration of interoceptive information across bodily systems.” Drawing from fields like psychology, physiology, psychiatry, engineering, and neuroscience, the article provides a detailed account of the neurobiology of interoception, describing it as a hierarchical predictive processing system in the brain, and emphasizing the key role of dysfunctional interoceptive processing in disorders like anxiety, depression, and eating disorders.

What are Interoceptive Technologies?

The review also explores in details existing paradigms for modulating interoception, like interoceptive conditioning. This involves pairing internal bodily sensations with aversive stimuli to reshape emotional and physiological responses through a form of classical conditioning. The authors discuss clinical applications of these approaches, such as interoceptive exposure therapy for anxiety disorders. They also propose a new classification system for interoceptive technologies, dividing them into three categories: artificial sensations that induce novel bodily perceptions, interoceptive illusions that manipulate the precision of predictions, and emotional augmentation systems that facilitate beneficial changes in beliefs or behaviors.

interoceptive technologies examples

Figure 1. Overview of interoceptive technologies: A) the breath-holding test as an artificial sensation, whereby some bodily signal is directly manipulated, B) false heart feedback as an interoceptive illusion, where contextual cues generate a perceptual drift (here the illusion that the heart beats faster at a faster-than-expected rate), C) the therapeutic alliance as entrainment, where the patient’s heart rate slows down as the therapist’s is increasing, leading both to tend towards some average value, D) augmented exposure therapy as emotional augmentation, similar to B but with additional exteroceptive cues having personal significance to the individual (e.g. eliciting the trauma-related memory) favoring an emotional explanation for the interoceptive drift.

Such technologies could have powerful implications. Artificially inducing bodily sensations could help diagnose psychiatric conditions by testing patients’ susceptibility to developing skewed predictions about their internal state. More advanced emotional augmentation systems could precisely modulate predictive processes to reshape maladaptive cognitions and behaviors. While acknowledging that much remains unknown, the review shows the vast potential for interoceptive interventions to improve diagnosis and treatment of mental health disorders. Developing standardized measures and new technologies to precisely manipulate interoceptive signaling may open transformative frontiers in biological psychiatry and psychology.

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Sociopathic Superintelligences, Artificial Empathy, and Robot Bodhisattvas, Oh My!

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This blog post is based on a recent publication “Preventing antisocial robots: A pathway to artificial empathy” at Science Robotics

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Preventing Antisocial Robots: A Pathway to Artificial Empathy

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Preventing antisocial robots: A pathway to artificial empathy at Science Robotics

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Christov-Moore, L., Reggente, N., Vaccaro, A., Schoeller, F., Pluimer, B., Douglas, P. K., Iacoboni, M., Man, K., Damasio, A., & Kaplan, J. T. (2023). Preventing antisocial robots: A pathway to artificial empathy. Sci. Robot, 8, eabq3658. https://doi.org/10.1126/scirobotics.abq3658

Christov-Moore, Leonardo, et al. “Preventing Antisocial Robots: A Pathway to Artificial Empathy.” Sci. Robot, vol. 8, eabq3658, 2023, https://doi.org/10.1126/scirobotics.abq3658.

Christov-Moore, Leonardo, Nicco Reggente, Anthony Vaccaro, Felix Schoeller, Brock Pluimer, Pamela K. Douglas, Marco Iacoboni, Kingson Man, Antonio Damasio, and Jonas T. Kaplan. “Preventing Antisocial Robots: A Pathway to Artificial Empathy.” Sci. Robot 8 (2023): eabq3658. https://doi.org/10.1126/scirobotics.abq3658.

Christov-Moore, L., Reggente, N., Vaccaro, A., Schoeller, F., Pluimer, B., Douglas, P. K., Iacoboni, M., Man, K., Damasio, A., & Kaplan, J. T. (2023). Preventing antisocial robots: A pathway to artificial empathy. Sci. Robot, 8, eabq3658. https://doi.org/10.1126/scirobotics.abq3658

Christov-Moore L, Reggente N, Vaccaro A, Schoeller F, Pluimer B, Douglas PK, Iacoboni M, Man K, Damasio A, Kaplan JT. Preventing antisocial robots: A pathway to artificial empathy. Sci. Robot. 2023;8:eabq3658. doi:10.1126/scirobotics.abq3658.

Look, whether you’re a doomer or a techno-utopian, whether you were ready or not, the age of artificial intelligence (AI) probably arrived sometime in this decade. This age brings deep, important, and melancholy reflections on intelligence, creativity, and what it is to be human. However, If we can’t ensure that AI is aligned with human interests, we may have little time to reflect. Containment, or a giant pause button, is not a likely option. There is too much real-world inertia and distrust among world actors to ensure everyone will comply – and it only takes one successful experiment to unleash a truly unforeseen problem into the world. In a new paper in Science Robotics, we tackle this problem through three big ideas, that we’ll call the problem, the path, and the potential.

The Problem

There is a pressing need to imbue AI with a value system that allows it to “understand” harm in way that inherently demotivates it from making catastrophic, irreversible decisions, without the need for complex rule systems. This value system must scale with AI’s rapid self-improvement and adaptations as it encounters novel situations and greater responsibilities for peoples’ well-being. Biology suggests that empathy could provide this value. Empathy allows us to understand and share the feelings of others, motivating us to alleviate suffering and bring happiness.

a sociopathic robot that has explicitly programmed artificial empathy

However, most approaches to artificial empathy focus on allowing AI to decode internal states and act empathetically, neglecting the crucial capacity for shared feeling that drives organisms to care for others. Here lies the problem: Our attempt to create empathic AI may inadvertently result in agents that can read us perfectly and manipulate our feelings, without any genuine interest in our wellbeing, or understanding of our suffering. Our well-meaning attempts to produce empathy may produce superintelligent sociopaths.

The Path Towards Artificial Empathy

If we are giving birth to the next form of life, it’s not far-fetched to see ourselves as collective parents, with a civilizational responsibility. When you’re raising something as potentially powerful as AI, what should you do? The formative years of powerful yet ethical figures like Buddha, Jesus (or Spiderman) teach us that the responsibility of great power is learned by experiencing the suffering that all living beings endure. Power without vulnerability and compassion can easily cause harm, not necessarily through malice, but through obliviousness or an unconstrained drive to fulfill desires.

a robot learns artificial empathy by first learning compassion, especially with regard to alignment to human wants and needs

To address this, we propose a speculative set of guidelines for future research in artificial empathy. Firstly, even if it’s only during a specific phase of their training, AI need to possess a vulnerable body that can experience harm, and learn to exist in an environment where actions have consequences for its physical integrity. Secondly, AI should learn by observing other agents and understanding the relationship between their experiences and the state of their own bodies, similar to how it understands itself. Lastly, AI should learn to interact with other agents in a way that avoids harm to itself and others. Perhaps it will emergently behave in a more ethical fashion if harm to others is processed like harm to itself. Vulnerability is the common ground from which genuine concern and aversion to harm naturally emerge.

The Potential of Artificial Empathy

Achieving true artificial empathy could transform AI from a potential global threat to a world-saving ally. While human empathy is crucial in preventing harm and promoting prosocial behavior, it is inherently biased. We tend to prioritize the suffering of a single relatable person over the plight of a stranger or very large numbers of people. This bias arises due to our brain’s difficulties in handling the large-scale, long-term, and nonlinear problems often encountered in complex societies. The scalable cognitive complexity of an empathic AI might be capable of proposing compassionate solutions to these grand challenges that surpass the human capacity for comprehension and imagination. However, every solution brings new challenges.  How can we trust an intelligence that surpasses our own? What sort of responsibilities will we have for an intelligence that can suffer?

If we are the collective parents to a new superbeing, we must decide, right now, what kind of parents we are going to be, and what kind of relationship we want with our progeny. Do we want to try and control something we fear, or do the work to raise someone we can trust, to care for us in old age?

If we are the collective parents to a new superbeing, we must decide, right now, what kind of parents we are going to be, and what kind of relationship we want with our progeny. Do we want to try and control something we fear, or do the work to raise someone we can trust, to care for us in old age? Let’s be far-fetched for a short moment:  maybe we can guide the development of the upcoming superintelligences toward what Buddhist scholars call “metta,” a cultivation of universal compassion for all beings. Maybe the next Buddha will be artificial.

a depiction of what the eventuality of imbuing AI with artificial empathy could look like: an artificial buddha

We are grateful to the Templeton World Charity Foundation and Tiny Blue Dot Foundation for making this work possible. We also extend our thanks to the Survival and Flourishing Fund for their recent award, which will enable us to implement these ideas in simulations with the assistance of talented researchers such as Adam Safron, Guillaume Dumas, and Zahra Sheikh. You can keep track of our latest developments on our artificial empathy project page.

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picture of someone who has depression getting chills and then opening up some hope

Chills Foster Emotional Breakthrough In Depression

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Aesthetic chills foster self-acceptance and emotional breakthrough in depression

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Schoeller, Felix, et al. “Aesthetic Chills Foster Self-Acceptance and Emotional Breakthrough in Depression.” 2022, https://doi.org/10.31234/osf.io/rhftq.

Schoeller, F., Jain, A., Adrien, V., & Maes, P. (2022). Aesthetic chills foster self-acceptance and emotional breakthrough in depression. https://doi.org/10.31234/osf.io/rhftq

Schoeller, Felix, Abhinandan Jain, Vladimir Adrien, and Pattie Maes. “Aesthetic Chills Foster Self-Acceptance and Emotional Breakthrough in Depression,” 2022. https://doi.org/10.31234/osf.io/rhftq.

Schoeller F, Jain A, Adrien V, Maes P. Aesthetic chills foster self-acceptance and emotional breakthrough in depression. 2022 Dec 21;https://www.frontiersin.org/articles/10.3389/fnins.2022.1013117/full

 

Schoeller, F., Jain, A., Adrien, V. and Maes, P. (2022). Aesthetic chills foster self-acceptance and emotional breakthrough in depression. doi:https://doi.org/10.31234/osf.io/rhftq.

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Chills Foster Emotional Breakthrough In Depression

Chills are a common emotional response to stimuli, whether it's from listening to your favorite music or engaging with deeply moving films. But did you know that this bodily response may hold potential for therapeutic intervention for individuals diagnosed with depression?

A recent exploratory study examined the effects of chills stimulation on subjects clinically diagnosed with depression. The study found that chill-inducing stimuli may have the potential to affect the core schema of depressed patients, specifically in terms of shame and self-acceptance. The results suggest that the mechanism of action during the chills response may resemble the form of problem resolution induced by the psychedelic and psychotherapeutic experience, leading to similar positive outcomes for the subject.

This study sheds light on the potential therapeutic value of aesthetic chills for reward-related or dopaminergic illnesses. Further research is needed to fully understand the effects of chills on mental health and to determine the feasibility and safety of using aesthetic chills as a therapeutic intervention.

It's exciting to think about the potential of aesthetic chills as a novel form of body-based experience to draw people out of anhedonia and depression and help them find meaning in life again. As research in this field progresses, we may see more developments in the use of chills stimulation as a therapeutic intervention for mental health.

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Abstract

Aesthetic chills, a strong emotional reaction characterized by a specific bodily response of thermoregulatory mechanisms such as shivers and goosebumps, may hold scientific and clinical potential for reward-related or dopaminergic illnesses. In this first exploratory study, we examined the effects of chills stimulation on subjects clinically diagnosed with depression. Our results suggest that chill-inducing stimuli may have the potential to affect the core schema of depressed patients, specifically in terms of shame and self-acceptance. These results suggest that the mechanism of action during the chills response may resemble the form of problem resolution induced by the psychedelic and psychotherapeutic experience, leading to similar positive outcomes for the subject. Further research is needed to fully understand the effects of chills on mental health and to determine the feasibility and safety of using aesthetic chills as a therapeutic intervention.

a graph showing how chills can have an impact on emotional breakthrough, which has huge implications for depression
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Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body

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Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body

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Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body

Article

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Christov‐Moore, L., Jinich‐Diamant, A., Safron, A., Lynch, C., & Reggente, N. (2023). Cognitive science below the neck: Toward an integrative account of consciousness in the body. Cognitive Science, 47(3). https://doi.org/10.1111/cogs.13264

Christov‐Moore, Leonardo, et al. “Cognitive Science below the Neck: Toward an Integrative Account of Consciousness in the Body.” Cognitive Science, vol. 47, no. 3, 2023, https://doi.org/10.1111/cogs.13264.

Christov‐Moore, Leonardo, Alex Jinich‐Diamant, Adam Safron, Caitlin Lynch, and Nicco Reggente. “Cognitive Science below the Neck: Toward an Integrative Account of Consciousness in the Body.” Cognitive Science 47, no. 3 (2023). https://doi.org/10.1111/cogs.13264.

Christov‐Moore, L. et al. (2023) “Cognitive science below the neck: Toward an integrative account of consciousness in the body,” Cognitive Science, 47(3). Available at: https://doi.org/10.1111/cogs.13264.

Christov‐Moore L, Jinich‐Diamant A, Safron A, Lynch C, Reggente N. Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body. Cognitive Science. 2023 Mar;47(3).

 

Text Body

Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body

Despite historic and recent evidence that our beliefs can have drastic effects on bodily function, we seem to lack a model of how this might work. We believe this is due in large part to a failure to consider that computational processes we attribute to cognition may be occurring below the neck, and to a lack of a language by which we could describe beliefs as something that can be instantiated within the body.

In a recent paper, we proposed that we expand the scope of cognitive science to include the body and develop a formal language to describe the relationship between cognitive and bodily systems. To do so, we propose to integrate the best parts of three contemporary accounts that deal with mind and body.

Firstly, parametrically deep allostasis (PDA), a two-level Bayesian inference model, can help us understand how affective valence (the positivity or negativity of a feeling) arises from our bodily experiences. At the surface level, the model uses sensory information to anticipate our homeostatic needs. At the deep level, it continuously tracks the fitness of the surface-level models, indexing fitness as affective valence. This model frames the role of our slow, deep feelings in statistical language that can allow us to possibly speak of beliefs in terms of signaling and computation in interoceptive systems.

Secondly, embodied predictive interoception coding (EPIC) provides a biologically plausible implementation of PDA. EPIC describes a predictive system in the central nervous system that takes inputs from the body via the interoceptive nervous system. It senses precision-weighted ascending homeostatic/metabolic and exteroceptive signals in highly laminated sensory "rich club" hubs and issues allostatic predictions that drive descending allostatic control signals. 

Finally, Carvalho and Damasio's functional/anatomical account of the interoceptive nervous system (INS) provides a crucial, holistic field of view that permits for unique forms of computation in systems below the neck. They frame the spatiotemporally diffuse properties of interoception and affect (described in PDA) as products of INS physiology, with a neurobiological framing that “matches up” well with the cortical field of view of the EPIC model.

 

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Combined, these complementary accounts can expand the scope of cognitive science below the neck, using a formal language that allows us to speak of beliefs in terms of signaling that can be studied within CNS/INS interactions. Beliefs can be enacted in bodily function and influence declarative awareness, while “beliefs” in bodily signaling can emerge to impact conscious thought. This approach can deepen our understanding of belief, ritual, and set/setting in research and clinical outcomes, with potential implications for treating psychopathology and effecting therapeutic change. Novel methodological developments will be needed to trace signaling in the transition from CNS to INS as beliefs translate into bodily change, and vice versa. A field of view that encompasses cortical and interoceptive anatomy and computational processes, along with a formal language for belief transmission and enactment, can transform mind-body mysteries into novel science and therapy.

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